Hong Kong News

Nonpartisan, Noncommercial, unconstrained.
Friday, Apr 26, 2024

Where did Covid-19 originate? These virus sleuths are assessing every theory

Where did Covid-19 originate? These virus sleuths are assessing every theory

Bat virus researcher leads Lancet-backed task force reviewing evidence on theories such as the outbreak coming from wildlife trade or existing first in Europe.

The origins of Covid-19remain unknown, and a gamut of hypotheses, conspiracy theories and studies have raised more questions than answers about how the virus that causes the disease emerged and spread around the world.

Now, a group of battle-tested disease detectives, led by a US-based scientist with a history researching bat viruses in China, are stepping up to evaluate “every hypothesis” for the source of this virus, first identified in the Chinese city of Wuhan nearly a year ago.

The task force was announced earlier this week under an interdisciplinary initiative backed by medical journal The Lancet to find solutions to the pandemic.

The formation of the Lancet Covid-19 Commission’s task force on the origins of the virus came just as another international effort to uncover the origins of the disease – the World Health Organization’s (WHO’s) scientific mission – was getting to work.

But unlike that inquiry, in which an international team will conduct research with Chinese scientists at the request of the WHO’s governing body, the Lancet task force is a public-facing group that does not expect to run its work on the ground in China, according to its leader, Peter Daszak, the bat virus researcher and president of US-based research organisation EcoHealth Alliance.

“We are scientists reviewing what’s known and saying, ‘Where does the evidence fall on the different hypotheses that are out there?’” said Daszak, who is in the unique position of being part of both the WHO international team and the Lancet task force.

“In one sense, [the Lancet team] will be freer to speak about our findings straight away and make them public.”

He said any public perception that an “international pathogen police force” was going to sweep in and find the equivalent of a smoking gun was unrealistic. In any such outbreak, finding out which animals the virus jumped from to get to humans could take years, and would require international scientists working together – something Daszak aims for the Lancet task force to promote.

“What we can do is bring people together who really know what happens in an outbreak, what happens in a biosafety lab, what happens with viral sequences and evolution … what happens in a wildlife market,” said the disease ecologist, known for his research on viral zoonosis.

Daszak, who declined to comment about the WHO mission for this story, is joined on the Lancet team by 11 other scientists who he says are well poised to take on the task.

Among them is Danielle Anderson, scientific director of the Duke-NUS Medical School’s biosafety level-3 laboratory, who has worked in the Wuhan Institute of Virology’s (WIV’s) high-containment lab.

There are also veterans of other outbreaks, including Sai Kit Lam of Universiti Malaya, who headed the team that discovered the deadly Nipah virus that emerged in Malaysia in 1998, as well as Hume Field of Australia’s University of Queensland and Hong Kong University’s Malik Peiris, who were both involved in key breakthroughs in China’s severe acute respiratory syndrome (Sars) epidemic nearly two decades ago.

The team will step into a complicated landscape, because the origins of the virus have become the object of intense global interest, prompting the flood of research and conflicting theories about where it came from, but few solid conclusions.

The scientific community generally agrees that the virus probably originated in a bat before passing to humans, perhaps via an intermediary host. Although many of the first known cases were linked to a Wuhan wet market, it is unknown whether the virus originated there – such as through infected animals sold in the wildlife trade – or was brought into the city from elsewhere.

The scientific question has turned into a political one, as Washington sought to pin blame for the subsequent pandemic on China. For a time, US officials pushed the idea, dismissed by most scientists, that the virus could have escaped in Wuhan from the WIV, which studies bat coronaviruses.

Daszak, who collaborated with the institute, had his own work caught up in the claims, as funding for his organisation’s research in China was cut by the US National Institutes of Health earlier this year.

The Chinese government has countered this message with its own line that even if the virus was identified in Wuhan, it did not necessarily originate there – although it has yet to release full findings from investigations in the city. A top Chinese Centre for Disease Control and Prevention official has also suggested that the virus could have originally arrived in China via imported seafood, without providing evidence.

Several controversial studies have also pointed to the possibility that the virus was circulating in Europe earlier than was originally known, adding another question about the timeline of the outbreak.

Daszak said that part of the Lancet task force’s work was to “look at every hypothesis, whether that’s this virus was circulating a year earlier in Europe, whether it’s that it came from a biosafety lab or the wildlife trade”.

For Daszak, who was part of a team along with WIV researchers who identified bats as reservoirs for Sars-like coronaviruses after the 2002-03 outbreak of that disease, the known evolutionary history of this lineage of coronaviruses points to a scenario in which this new and related coronavirus originated in the same region.

Although the closest known relative to the novel coronavirus was found in a cave in southwest China’s Yunnan province, the horseshoe bat species that carries it has a range across Southeast Asia. Less sampling of coronaviruses in bats has been done in China’s neighbouring countries of Myanmar, Vietnam and Laos, according to Daszak.

“It’s quite possible that the origin of Sars-CoV-2 is outside China in that sense, that it’s in a bat or a colony of bats or a species and it evolved somewhere in a neighbouring country in Southeast Asia,” he said. “But to say that it may have evolved in Italy or Spain, I don’t think that’s plausible.

“But we are going to keep an open mind on the task force, and look at the evidence,” he said, adding that what the Lancet team finds could help guide ongoing research.

Apart from analysing the available evidence, the task force will seek to interview researchers in China. There are no mainland Chinese scientists on the Lancet team.

“The only question is whether it’s too sensitive to talk about, but I’m hoping that over time it will become a lot more straightforward and open and less political,” he said. “I think the politics really messes this up – that’s one of the problems.”

The stakes are high for finding answers. Daszak’s own research shows disease outbreaks are happening with increasing frequency – a symptom of land use changes, wildlife trade, and global trade and consumption patterns, he said.

“If we don’t understand better what’s happened, and use that to prevent what’s going to happen,” he said, “we’re never going to dig our way out of the pandemic era.”

Newsletter

Related Articles

Hong Kong News
0:00
0:00
Close
It's always the people with the dirty hands pointing their fingers
Paper straws found to contain long-lasting and potentially toxic chemicals - study
FTX's Bankman-Fried headed for jail after judge revokes bail
Blackrock gets half a trillion dollar deal to rebuild Ukraine
Steve Jobs' Son Launches Venture Capital Firm With $200 Million For Cancer Treatments
Google reshuffles Assistant unit, lays off some staffers, to 'supercharge' products with A.I.
End of Viagra? FDA approved a gel against erectile dysfunction
UK sanctions Russians judges over dual British national Kara-Murza's trial
US restricts visa-free travel for Hungarian passport holders because of security concerns
America's First New Nuclear Reactor in Nearly Seven Years Begins Operations
Southeast Asia moves closer to economic unity with new regional payments system
Political leader from South Africa, Julius Malema, led violent racist chants at a massive rally on Saturday
Today Hunter Biden’s best friend and business associate, Devon Archer, testified that Joe Biden met in Georgetown with Russian Moscow Mayor's Wife Yelena Baturina who later paid Hunter Biden $3.5 million in so called “consulting fees”
'I am not your servant': IndiGo crew member, passenger get into row over airline meal
Singapore Carries Out First Execution of a Woman in Two Decades Amid Capital Punishment Debate
Spanish Citizenship Granted to Iranian chess player who removed hijab
US Senate Republican Mitch McConnell freezes up, leaves press conference
Speaker McCarthy says the United States House of Representatives is getting ready to impeach Joe Biden.
San Francisco car crash
This camera man is a genius
3D ad in front of Burj Khalifa
Next level gaming
BMW driver…
Google testing journalism AI. We are doing it already 2 years, and without Google biased propoganda and manipulated censorship
Unlike illegal imigrants coming by boats - US Citizens Will Need Visa To Travel To Europe in 2024
Musk announces Twitter name and logo change to X.com
The politician and the journalist lost control and started fighting on live broadcast.
The future of sports
Unveiling the Black Hole: The Mysterious Fate of EU's Aid to Ukraine
Farewell to a Music Titan: Tony Bennett, Renowned Jazz and Pop Vocalist, Passes Away at 96
Alarming Behavior Among Florida's Sharks Raises Concerns Over Possible Cocaine Exposure
Transgender Exclusion in Miss Italy Stirs Controversy Amidst Changing Global Beauty Pageant Landscape
Joe Biden admitted, in his own words, that he delivered what he promised in exchange for the $10 million bribe he received from the Ukraine Oil Company.
TikTok Takes On Spotify And Apple, Launches Own Music Service
Global Trend: Using Anti-Fake News Laws as Censorship Tools - A Deep Dive into Tunisia's Scenario
Arresting Putin During South African Visit Would Equate to War Declaration, Asserts President Ramaphosa
Hacktivist Collective Anonymous Launches 'Project Disclosure' to Unearth Information on UFOs and ETIs
Typo sends millions of US military emails to Russian ally Mali
Server Arrested For Theft After Refusing To Pay A Table's $100 Restaurant Bill When They Dined & Dashed
The Changing Face of Europe: How Mass Migration is Reshaping the Political Landscape
China Urges EU to Clarify Strategic Partnership Amid Trade Tensions
The Last Pour: Anchor Brewing, America's Pioneer Craft Brewer, Closes After 127 Years
Democracy not: EU's Digital Commissioner Considers Shutting Down Social Media Platforms Amid Social Unrest
Sarah Silverman and Renowned Authors Lodge Copyright Infringement Case Against OpenAI and Meta
Why Do Tech Executives Support Kennedy Jr.?
The New York Times Announces Closure of its Sports Section in Favor of The Athletic
BBC Anchor Huw Edwards Hospitalized Amid Child Sex Abuse Allegations, Family Confirms
Florida Attorney General requests Meta CEO's testimony on company's platforms' alleged facilitation of illicit activities
The Distorted Mirror of actual approval ratings: Examining the True Threat to Democracy Beyond the Persona of Putin
40,000 child slaves in Congo are forced to work in cobalt mines so we can drive electric cars.
×