Several nightclub-related coronavirus clusters in a popular entertainment district continued to worsen on Saturday, while Hong Kong’s commerce minister called for a “prudent” approach when the city eventually opened up to the rest of the world.

The city reported 446 new Covid-19 infections, 64 of which were imported, and no additional coronavirus-related fatalities. Health officials said they expected to uncover more cases connected to the four clusters after compulsory testing was completed.

The overall tally of confirmed cases stands at 1,214,638, with the death toll remaining at 9,382.