Devastating images from the scene showed smoke billowing into the sky from several trucks on fire in the wake of multiple crashes which happened within 10 minutes on Saturday evening.
Seven people were killed in a single collision on the highway in Changsha, the capital of China’s south-central Hunan province.
More than 180 rescue workers were deployed to the scene, according to reports in Chinese state media.
A total of 66 people have so far been reported injured, authorities said on Sunday.
Eight people suffered ‘relatively severe’ injuries, but are currently stable, a traffic police spokesperson said, adding: ‘Those injured were promptly sent to hospital for thorough treatment.’
China’s emergency management ministry has called for an investigation into the cause of the tragedy.